Welcome to the Gronert Lab!

Mission Statement

Research efforts in the Gronert laboratory are part of a new paradigm that has established lipid networks as critical regulators for the successful execution of healthy immune responses and for maintaining tissue homeostasis. Our research focused on elucidating the role of these endogenous protective networks in ocular immune and reparative responses and retinal neurodegeneration. The endogenous role of these clinically important lipid mediators and their receptors is rapidly evolving but many questions about their regulation and molecular mechanisms of action remain to be answered.

Our laboratory employs innovative approaches and state-of-the art technology to discover and define the regulation of protective lipid mediator networks at the gene, enzyme, receptor and cell level. A long-standing expertise of our research group is LC/MS/MS-based lipidomics and lipid mediator bioinformatics. Our long-term goals are aimed at defining the regulation of lipid mediator programs in health and understand how they are dysregulated in diseases in order to develop innovative approaches for their therapeutic amplification.